BIND® Technology

Label-free technology IN A MICROPLATE FORMAT FOR SMALL MOLECULE, PROTEIN, AND CELL INTERACTIONS

Benefits of the BIND Technology

Label-free detection
High throughput
Simplified assay development
Universal assay platform for cells, proteins and small molecules
Industry standard formats
Substantial cost savings

BIND® from SRU Biosystems is a universal assay system that enables label-free detection of drug-target interactions. The system is comprised of the BIND® Reader and 96-, 384- or 1536-well microplate BIND® Biosensors. The BIND system takes advantage of a novel optical effect to provide very sensitive measurements of changes in binding or adherence in the proximity of the biosensor surface. The biosensor incorporates a proprietary nanostructured optical grating, and is incorporated in microwell plates in industry standard formats. The BIND system delivers higher quality assay data and improved throughput, both resulting in cost savings.

Click to enlarge

BIND® Principles

The grating of the BIND biosensor reflects only a single wavelength (“Peak Wavelength Value” or “PWV”). When a biomolecule or cell binds to the biosensor surface, this reflected wavelength increases. Real time binding can be observed by measurement of the shift in PWV over time. Both biochemical and cell-based assays are easy with BIND. For example, when an antibody is immobilized on the biosensor surface, antigen binding can be detected without the use of a label. Each addition of an assay component to a well can be observed in real time to monitor the interaction formation and dissociation, differentiating both specific and nonspecific interactions and enhancing both assay development and screening quality control. BIND is a powerful development tool that lets you qualify and quantify binding at every step of your experiment.

Visit our Founder, Brian Cunningham's website at University of Illinois at Urbana-Champaign for the latest in biosensor research and additional publications on BIND technology. http://nano.ece.uiuc.edu



Applications Products Technology Company Management Team & Board of Directors News Employment Company Overview Technology Overview Publications Products Overview BIND® Reader • Software • Specifications BIND® Biosensor Download Literature ComBIND™ Microarray Slide Applications Overview Cell based assays Direct binding small molecule assays Antibody screening


BIND® Technology Label-free technology IN A MICROPLATE FORMAT FOR SMALL MOLECULE, PROTEIN, AND CELL INTERACTIONS Benefits of the BIND Technology Label-free detection High throughput Simplified assay development Universal assay platform for cells, proteins and small molecules Industry standard formats Substantial cost savings BIND® from SRU Biosystems is a universal assay system that enables label-free detection of drug-target interactions. The system is comprised of the BIND® Reader and 96-, 384- or 1536-well microplate BIND® Biosensors. The BIND system takes advantage of a novel optical effect to provide very sensitive measurements of changes in binding or adherence in the proximity of the biosensor surface. The biosensor incorporates a proprietary nanostructured optical grating, and is incorporated in microwell plates in industry standard formats. The BIND system delivers higher quality assay data and improved throughput, both resulting in cost savings. Click to enlarge BIND® Principles The grating of the BIND biosensor reflects only a single wavelength (“Peak Wavelength Value” or “PWV”). When a biomolecule or cell binds to the biosensor surface, this reflected wavelength increases. Real time binding can be observed by measurement of the shift in PWV over time. Both biochemical and cell-based assays are easy with BIND. For example, when an antibody is immobilized on the biosensor surface, antigen binding can be detected without the use of a label. Each addition of an assay component to a well can be observed in real time to monitor the interaction formation and dissociation, differentiating both specific and nonspecific interactions and enhancing both assay development and screening quality control. BIND is a powerful development tool that lets you qualify and quantify binding at every step of your experiment. Visit our Founder, Brian Cunningham's website at University of Illinois at Urbana-Champaign for the latest in biosensor research and additional publications on BIND technology. http://nano.ece.uiuc.edu

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